PA124763

FGFR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA124763-Each-of-1 In Stock ₹ 46,680.50

PA124763 - Each of 1

₹ 46,680.50

In Stock

Quantity

1

Base Price: ₹ 46,680.50

GST (18%): ₹ 8,402.49

Total Price: ₹ 55,082.99

Antigen

FGFR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FGFR2

Gene Alias

AU043015; AW556123; bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; ECT1; FGF Receptor 2; FGF-10; FGFR2; FGFR-2; Fgfr7; Fgfr-7; fibroblast growth factor receptor 2; JWS; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; protein tyrosine kinase, receptor like 14; Soluble KGFR; svs; TK14; TK25

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14183, 2263

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.3 mg/mL

Formulation

0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P21802, P21803

Gene Symbols

FGFR2

Immunogen

Synthetic peptide, conjugated to KLH by a Glutaraldehyde linker, corresponding to residues K(809) L P Q Y P H I G S V K T(821) of the cytoplasmic region of Human FGFR2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody shows no cross reactivity with FGFR1 or FGFR3
  • PA1-24763 is expected to cross react with mouse (92% conserved) and rat (92% conserved) due to sequence homology
  • FGFR2 is a member of the FGFR family of receptor tyrosine kinases
  • This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury
  • The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy
  • FGFR family members differ from one another in their ligand affinities and tissue distribution
  • Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis
  • Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.