PA130332

SP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA130332-Each-of-1 In Stock ₹ 52,332.00

PA130332 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

SP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SP1

Gene Alias

1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20683, 24790, 6667

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with 0.2% gelatin and 0.1% sodium azide

Gene Accession No.

O89090, P08047, Q01714

Gene Symbols

SP1

Immunogen

Synthetic peptide (Internal sequence).

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-30332 detects SP1 from human, rat, mouse samples
  • SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
  • Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses
  • Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation)
  • Binds also the PDGFR-alpha G-box promoter
  • May have a role in modulating the cellular response to DNA damage
  • Implicated in chromatin remodeling
  • Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter
  • Plays an essential role in the regulation of FE65 gene expression.