PA131072

SOD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA131072-Each-of-1 In Stock ₹ 51,798.00

PA131072 - Each of 1

₹ 51,798.00

In Stock

Quantity

1

Base Price: ₹ 51,798.00

GST (18%): ₹ 9,323.64

Total Price: ₹ 61,121.64

Antigen

SOD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SOD2

Gene Alias

I79_015272; indophenoloxidase B; IPO B; IPOB; IPO-B; manganese SOD; manganese superoxide dismutase; manganese-containing superoxide dismutase; mangano-superoxide dismutase; manganous superoxide dismutase; mitochondrial superoxide dismutase 2; Mn superoxide dismutase; MNSOD; Mn-SOD; MVCD6; similar to manganous superoxide dismutase; Sod2; Sod-2; sod2.L; sodMt; Superoxide dimutase 2, mitochondrial; superoxide dismutase; superoxide dismutase (Mn type); superoxide dismutase [Mn], mitochondrial; superoxide dismutase 2; superoxide dismutase 2 L homeolog; superoxide dismutase 2, mitochondrial; superoxide dismutase 2, mitochondrial L homeolog

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100154319, 100760320, 103349944, 104973000, 20656, 24787, 281496, 399216, 476258, 6648, 780457

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

0.05M sodium phosphate with 0.1% BSA, 50% glycerol and 0.1% sodium azide; pH 7.2

Gene Accession No.

P04179, P07895, P09671, P28768, P41976, P41982, P54712

Gene Symbols

SOD2, sod2.L

Immunogen

Full length protein (Human).

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Hamster, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat, X. laevis

Product Type

Antibody

Isotype

IgG

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Description

  • Rat brain tissue extract was used as a positive control
  • Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS)
  • SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase
  • Several classes of SOD have been identified
  • These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3)
  • SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit
  • The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain
  • SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways
  • SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase
  • CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.