PA14180

SHANK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA14180-Each-of-1 In Stock ₹ 46,502.50

PA14180 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

SHANK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SHANK1

Gene Alias

GKAP/SAPAP interacting protein; GKAP/SAPAP-interacting protein; OTTHUMP00000174437; SAPAP-interacting protein synamon; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains protein 1; SH3/ankyrin domain gene 1; SHANK 1; Shank1; Shank1a; somatostatin receptor-interacting protein; SPANK 1; Spank1; SPANK-1; SSTR-interacting protein; Sstrip; Synamon

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

243961, 50944, 78957

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

D3YZU1, Q9WV48, Q9Y566

Gene Symbols

SHANK1

Immunogen

Synthetic peptide corresponding to the C-terminal residues S(1951) G P I Y P G L F D I R S S(1964) of rat Shank1a.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-4180 detects SHANK1a in human, rat, and mouse samples
  • PA1-4180 has been successfully used in Western blot, immunofluorescence, and immunofluoresence procedures
  • By Western blot this antibody detects a ∽212 kDa protein representing SHANK1a in rat brain lysate
  • The PA1-4180 immunogen is a synthetic peptide corresponding to the C-terminal residues S(1951) G P I Y P G L F D I R S S(1964) of rat Shank1a
  • Maintain at 4oC for 3 months or at -20oC for longer periods
  • Avoid freeze/thaw cycles
  • Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton
  • May play a role in the structural and functional organization of the dendritic spine and synaptic junction.