PA540169

Phospho-ATR (Ser428) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540169-Each-of-1 In Stock ₹ 48,104.50

PA540169 - Each of 1

₹ 48,104.50

In Stock

Quantity

1

Base Price: ₹ 48,104.50

GST (18%): ₹ 8,658.81

Total Price: ₹ 56,763.31

Antigen

Phospho-ATR (Ser428)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATR

Gene Alias

2310008J16Rik; 2810405N18Rik; ataxia telangiectasia and Rad3 related; ataxia telangiectasia and Rad3-related protein; ATR; ATR serine/threonine kinase; EC 2.7.11.1; FCTCS; FRAP-related protein 1; FRAP-related protein-1; FRP1; I79_000761; kinase ATR; MEC1; MEC1, mitosis entry checkpoint 1, homolog; protein kinase ATR; SCKL; SCKL1; Serine/threonine-protein kinase ATR; TEM8

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

545

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q13535

Gene Symbols

ATR

Immunogen

Peptide sequence around phosphorylation site of serine 428 (G-I-S(p)-P-K) derived from Human ATR.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress
  • The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis
  • This protein is also important for fragile site stability and centrosome duplication
  • Defects in this gene are a cause of Seckel syndrome 1.