PA1726

PDE6D Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1726-Each-of-1 In Stock ₹ 46,324.50

PA1726 - Each of 1

₹ 46,324.50

In Stock

Quantity

1

Base Price: ₹ 46,324.50

GST (18%): ₹ 8,338.41

Total Price: ₹ 54,662.91

Antigen

PDE6D

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PDE6D

Gene Alias

AI841218; GMP-PDE delta; JBTS22; PDE6D; PDED; phosphodiesterase 6D; phosphodiesterase 6D, cGMP-specific, rod, delta; PrBP/delta; Protein p17; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; rod phosphodiesterase delta subunit

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

101108369, 281976, 5147

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

O43924, Q95142

Gene Symbols

PDE6D

Immunogen

Synthetic Peptides: M(1) S A K D E R A R (D/E) I L R G F K(16) C

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Ovine

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-726 detects PrBP/delta from bovine, human and sheep samples
  • PA1-726 has been successfully used in Western blot, ICC/IF and immunohistochemistry procedures
  • By Western blot, this antibody detects a 17 kDa protein representing PrBP/delta from bovine and sheep retinal/optic nerve extracts as well as HeLa cell lysate
  • Immunohistochemical staining of PrBP/delta in bovine retinal cross-sections using PA1-726 results in staining of retinal outer segments
  • PA1-726 immunizing peptides correspond to amino acid residues 1-16 from mouse and human PrBP/delta
  • This peptide (Cat
  • # PEP-203) is available for use in neutralization and control experiments
  • PrBP/delta, previously known as PDE6/delta, is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system
  • There are five different subunits consisting of rod and cone specific catalytic subunits: alpha (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family)
  • PRBP/delta has been implicated in the transport and membrane targeting of prenylated proteins (including PDE6) from their site of synthesis in the inner segment to their final destination in the outer segment of rods and cones (Norton et
  • al., 2005).