VAMP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1766-Each-of-1 | In Stock | ₹ 49,751.00 |
PA1766 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,751.00
GST (18%): ₹ 8,955.18
Total Price: ₹ 58,706.18
Antigen
VAMP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
VAMP2
Gene Alias
RATVAMPB; RATVAMPIR; SYB; SYB2; Syb-2; sybII; Synaptobrevin; synaptobrevin 2; Synaptobrevin 2 (vesicle-associated membrane protein VAMP-2); synaptobrevin II; synaptobrevin-2; vamp; Vamp2; VAMP-2; vesicle associated membrane protein 2; vesicle-associated membrane 2; Vesicle-associated membrane protein (synaptobrevin 2); vesicle-associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22318, 24803
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P63044, P63045
Gene Symbols
VAMP2
Immunogen
Synthetic peptide corresponding to residues M(1) S A T A A T V P P A A P A G E G G(18) C of rat VAMP-2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-766 detects vesicle associated membrane protein 2 (VAMP-2) from rat and mouse tissues
- PA1-766 has been successfully used in Western blot, immunofluorescence, and immunoprecipitation procedures
- By Western blot, this antibody detects a 19 kDa protein representing VAMP-2 from rat brain whole protein extract
- The PA1-766 immunogen is a synthetic peptide corresponding to residues M(1) S A T A A T V P P A A P A G E G G(18) C of rat VAMP-2
- This immunizing peptide (Cat
- # PEP-101) is available for use in neutralization and control experiments
- The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes
- VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP
- These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane
- The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP
- In Alzheimer's disease, VAMP levels of all isoforms appear to be significantly lowered
- It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.