RAB8A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550483-Each-of-1 | In Stock | ₹ 48,104.50 |
PA550483 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,104.50
GST (18%): ₹ 8,658.81
Total Price: ₹ 56,763.31
Antigen
RAB8A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RAB8A
Gene Alias
AA409338; cell line NK14 derived transforming oncogene; MEL; mel transforming oncogene (derived from cell line NK14); mel transforming oncogene (derived from cell line NK14)- RAB8 homolog; mel transforming oncogene (RAB8 homolog); oncogene c-mel; Rab8; Rab8a; RAB8A, member RAS oncogene family; ras-associated protein RAB8; ras-related protein Rab-8A
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4218
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
0.7 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P61006
Gene Symbols
RAB8A
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human Ras-related protein Rab-8A
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total RAB8A protein
- The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids
- The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane
- This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins
- The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins
- However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins
- Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable
- This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.