PTPN13 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA550660-Each-of-1 | In Stock | ₹ 46,502.50 |
PA550660 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
PTPN13
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPN13
Gene Alias
AI324989; DKFZp686J1497; FAP-1; Fas-associated protein-tyrosine phosphatase 1; hPTP1E; hPTPE1; PNP1; protein Tyr phosphatase; protein tyrosine phosphatase DPZPTP; Protein tyrosine phosphatase PTP-BL; protein tyrosine phosphatase, non-receptor type 13; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase); protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; protein-tyrosine phosphatase RIP; ptp; Ptp14; PTP1E; PTP36; PTP-BAS; PTP-BL; PTP-E1; PTPL1; PTPLE; PTPN13; Ptpri; RIP; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 13
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5783
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1.8 mg/mL
Formulation
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q12923
Gene Symbols
PTPN13
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody detects endogenous levels of total PTPN13 protein
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
- PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
- This PTP is a large intracellular protein
- It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements
- This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains
- This suggests it has a role in Fas mediated programmed cell death
- This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways
- Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.