Desmin Monoclonal Antibody (D33), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA513259-Each-of-1 | In Stock | ₹ 48,460.50 |
PIMA513259 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,460.50
GST (18%): ₹ 8,722.89
Total Price: ₹ 57,183.39
Antigen
Desmin
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4
Gene Accession No.
O62654, P02542, P17661, P48675, Q5XFN2
Gene Symbols
DES
Immunogen
Desmin from human muscle
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Bovine, Canine, Chicken, Feline, Hamster, Human, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
D33
Conjugate
Unconjugated
Gene
DES
Gene Alias
CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
100764990, 101097010, 1674, 280765, 395906, 497091, 64362
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-13259 targets Desmin in IF and IHC (P) applications and shows reactivity with Bovine, Canine, Chicken, Feline, Hamster, Human, Non-human primate, and Rat samples
- The MA5-13259 immunogen is desmin from human muscle
- Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle)
- Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation
- In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk
- The expression pattern of desmin in smooth muscle is much more heterogenous
- Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue, i.e
- rhabdomyosarcomas and leiomyosarcomas
- Furthermore, during myocard dysfunction dramatic changes in the distribution of desmin have been observed.