Vimentin Antibody Cocktail, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514435-Each-of-1 | In Stock | ₹ 51,931.50 |
PIMA514435 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,931.50
GST (18%): ₹ 9,347.67
Total Price: ₹ 61,279.17
Antigen
Vimentin
Classification
Cocktail
Conjugate
Unconjugated
Gene
Vim
Gene Alias
cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus
Host Species
Mixed
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
7431
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
Vimentin-SP20, gp100-HMB45, gp100-HMB45
Formulation
proprietary buffer with <0.1% sodium azide
Gene Accession No.
P08670
Gene Symbols
Vim
Immunogen
Vimentin - recombinant protein encoding human Vimentin, gp100 - Extract of pigmented melanoma metastases from lymph nodes
Quantity
7 mL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- MA5-14435 targets Vimentin in IHC (P) applications and shows reactivity with Human samples
- The MA5-14435 immunogen is vimentin - recombinant protein encoding human Vimentin, gp100 - Extract of pigmented melanoma metastases from lymph nodes
- Host/Isotype: Rabbit/Mouse / IgG/IgG1, kappa Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin
- It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane
- Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development
- During the development process, vimentin is exchanged for new, tissue-specific IFPs
- Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets
- Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event
- This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.