CDK2 Monoclonal Antibody (SP80), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516346-Each-of-1 | In Stock | ₹ 59,541.00 |
PIMA516346 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,541.00
GST (18%): ₹ 10,717.38
Total Price: ₹ 70,258.38
Antigen
CDK2
Classification
Monoclonal
Concentration
0.031 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.6
Gene Accession No.
P24941, P97377, Q63699
Gene Symbols
CDK2
Immunogen
Synthetic peptide corresponding to C-terminus of human CDK2 protein.
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
SP80
Conjugate
Unconjugated
Gene
CDK2
Gene Alias
A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
1017, 12566, 362817
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- Heat-mediated antigen retrieval is recommended prior to staining, using a 1mM EDTA buffer, pH 8.0, for 10 minutes followed by cooling at room temperature for 20 min
- Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
- A suggested positive control is tonsil tissue (IHC) or Hela lysate (WB)
- CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO
- CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus
- In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity
- CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle
- The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication
- Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo
- Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.