PIMA515356

DDR2 Monoclonal Antibody (3B11E4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515356-Each-of-1 In Stock ₹ 52,732.50

PIMA515356 - Each of 1

₹ 52,732.50

In Stock

Quantity

1

Base Price: ₹ 52,732.50

GST (18%): ₹ 9,491.85

Total Price: ₹ 62,224.35

Antigen

DDR2

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.03% sodium azide

Gene Accession No.

Q16832

Gene Symbols

Ddr2

Immunogen

Purified recombinant fragment of human DDR2 expressed in E. Coli.

Regulatory Status

RUO

Gene ID (Entrez)

4921

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

3B11E4

Conjugate

Unconjugated

Gene

Ddr2

Gene Alias

AW495251; CD_antigen: CD167b; CD167 antigen-like family member B; CD167b; CD167b antigen; cell migration-inducing protein 20; Ddr2; Discoidin domain receptor 2; discoidin domain receptor family, member 2; discoidin domain receptor tyrosine kinase 2; discoidin domain-containing receptor 2; Discoidin domain-containing receptor tyrosine kinase 2; hydroxyaryl-protein; hydroxyaryl-protein kinase; MIG20a; migration-inducing gene 16 protein; neurotrophic tyrosine kinase receptor related 3; neurotrophic tyrosine kinase, receptor-related 3; Ntrkr3; receptor protein-tyrosine kinase TKT; RP11-572K18.1; TKT; TYRO10; tyrosine-protein kinase TYRO 10; tyrosine-protein kinase TYRO10; tyrosylprotein kinase

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a

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Description

  • MA5-15356 targets DDR2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples
  • The MA5-15356 immunogen is purified recombinant fragment of human DDR2 expressed in E
  • Coli
  • DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain
  • DDR1 and DDR2 have been shown to be potently inhibited by Gleevec
  • DDR2 required for normal bone development
  • Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2
  • Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion
  • Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.