TNNI2 Monoclonal Antibody (2F12A11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515911-Each-of-1 | In Stock | ₹ 50,062.50 |
PIMA515911 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,062.50
GST (18%): ₹ 9,011.25
Total Price: ₹ 59,073.75
Antigen
TNNI2
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.03% sodium azide
Gene Accession No.
P02643, P13412, P48788
Gene Symbols
Tnni2
Immunogen
Purified recombinant fragment of human TNNI2 expressed in E. Coli.
Regulatory Status
RUO
Gene ID (Entrez)
100009581, 21953, 7136
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone
2F12A11
Conjugate
Unconjugated
Gene
Tnni2
Gene Alias
AMCD2B; DA2B; FSSV; fsTnI; TnI; TNNI2; troponin 1, type 2; troponin I; troponin I fast twitch 2; troponin I type 2 (skeletal, fast); troponin I, fast skeletal muscle; Troponin I, fast-twitch isoform; troponin I, fast-twitch skeletal muscle isoform; troponin I, skeletal, fast; troponin I, skeletal, fast 2; troponin I2, fast skeletal type; Trp1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rabbit
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-15911 targets TNNI2 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples
- The MA5-15911 immunogen is purified recombinant fragment of human TNNI2 expressed in E
- Coli
- MA5-15911 detects TNNI2 which has a predicted molecular weight of approximately 21kDa
- This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits
- The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction
- Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function
- In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha
- This protein also suppresses tumor growth in human ovarian carcinoma
- Mutations in this gene cause myopathy and distal arthrogryposis type 2B
- Alternatively spliced transcript variants have been found for this gene.