Lamin A/C (R482W) Monoclonal Antibody (5H8-B4), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA518063-Each-of-1 | In Stock | ₹ 49,884.50 |
PIMA518063 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,884.50
GST (18%): ₹ 8,979.21
Total Price: ₹ 58,863.71
Antigen
Lamin A/C (R482W)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
P02545
Gene Symbols
LMNA
Immunogen
Lamin A Ig-fold, human (Immunogen sequence: 430-545 (6xHis-tagged fusion protein))
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
5H8-B4
Conjugate
Unconjugated
Gene
LMNA
Gene Alias
70 kDa lamin, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, lamin, lamin A/C, lamin A/C-like 1, Lamin-A/C, LDP1, LFP, LGMD1B, LMN1, LMNA, LMNC, LMNL1, Prelamin-A/C, PRO1, Renal carcinoma antigen NY-REN-32
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4000
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody recognizes the FPLD-associated lamin A/C mutant strain R482W
- Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope
- These proteins are found in many different cell types in three different forms (A, B, and C)
- Lamins A and C are alternatively spliced versions of the LMNA gene
- The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).