PIMA524587

Aquaporin 4 Monoclonal Antibody (CL0178), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524587-Each-of-1 In Stock ₹ 53,400.00

PIMA524587 - Each of 1

₹ 53,400.00

In Stock

Quantity

1

Base Price: ₹ 53,400.00

GST (18%): ₹ 9,612.00

Total Price: ₹ 63,012.00

Antigen

Aquaporin 4

Classification

Monoclonal

Concentration

1.00 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P55087

Gene Symbols

AQP4

Immunogen

Recombinant protein corresponding to Human Aquaporin 4

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry, Western Blot

Clone

CL0178

Conjugate

Unconjugated

Gene

AQP4

Gene Alias

Aqp4; AQP-4; aquaporin 4; aquaporin type4; Aquaporin4; aquaporin-4; HMIWC2; Mercurial-insensitive water channel; MGC22454; MIWC; MIWC2; WCH4

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

361

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: CPDVEFKRRF KEAFSKAAQQ TKGSYMEVED NRSQVETDDL ILKPGVVHVI DVDRGEEKKG KDQSGEVLSS V Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%
  • Binds to an epitope located within the peptide sequence FKRRFKEAFS as determined by overlapping synthetic peptides
  • In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers
  • Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane
  • This function is conserved in animals, plants and bacteria
  • Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10
  • Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell
  • Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol.