PIMA524804
IL23R Monoclonal Antibody (15N6C6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524804-Each-of-1 | In Stock | ₹ 47,926.50 |
PIMA524804 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,926.50
GST (18%): ₹ 8,626.77
Total Price: ₹ 56,553.27
Antigen
IL23R
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.
Q5VWK5
Gene Symbols
Il23r
Immunogen
Synthetic peptide corresponding to amino acids 288-315 of Human IL-23 receptor.
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
15N6C6
Conjugate
Unconjugated
Gene
Il23r
Gene Alias
IBD17; IL 23R; IL-23 receptor; IL23R; IL-23R; interleukin 23 receptor; interleukin 23 receptor-like; interleukin-23 receptor
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
149233
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling
- Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner
- Alternative splicing results in six spliced isoforms of IL-23R
- Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.