Fe65 Monoclonal Antibody (OTI3H9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527408-Each-of-1 | In Stock | ₹ 52,287.50 |
PIMA527408 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,287.50
GST (18%): ₹ 9,411.75
Total Price: ₹ 61,699.25
Antigen
Fe65
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O00213
Gene Symbols
APBB1
Immunogen
Full length human recombinant protein of APBB1 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
OTI3H9
Conjugate
Unconjugated
Gene
APBB1
Gene Alias
adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); amyloid beta A4 precursor protein-binding family B member 1; amyloid beta precursor protein binding family B member 1; Amyloid-beta A4 precursor protein-binding family B member 1; APBB1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
322
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The protein encoded by this gene is a member of the Fe65 protein family
- It is an adaptor protein localized in the nucleus
- It interacts with the Alzheimer's disease amyloid precursor protein, transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein
- APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation
- This encoded protein could play an important role in the pathogenesis of Alzheimer's disease
- It is thought to regulate transcription
- Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression
- Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.