TRIM25 Monoclonal Antibody (5B5B12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA531935-Each-of-1 | In Stock | ₹ 49,795.50 |
PIMA531935 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,795.50
GST (18%): ₹ 8,963.19
Total Price: ₹ 58,758.69
Antigen
TRIM25
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q14258, Q61510
Gene Symbols
TRIM25
Immunogen
Purified recombinant fragment of human TRIM25 (AA: 211-360) expressed in E. coli.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
5B5B12
Conjugate
Unconjugated
Gene
TRIM25
Gene Alias
AA960166; AL022677; E3 ubiquitin/ISG15 ligase TRIM25; Efp; Estrogen-responsive finger protein; RING finger protein 147; RING-type E3 ubiquitin transferase; RING-type E3 ubiquitin transferase TRIM25; RNF147; Trim25; tripartite motif containing 25; tripartite motif protein 25; tripartite motif protein TRIM25; tripartite motif-containing 25; tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Z147; Zfp147; Zinc finger protein 147; zinc finger protein 147 (estrogen-responsive finger protein); zinc finger protein-147; Znf147
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
217069, 7706
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-31935 has been tested in indirect ELISA
- TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family and is a downstream target of estrogen receptor a
- Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demonstrating that this protein is essential for estrogen dependent proliferation
- TRIM25 expression is increased in breast carcinoma where it promotes the growth of breast tumor by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3s
- Recent reports have indicated that TRIM25 E3 ubiquitin ligase is essential for the retinoic-acid-inducible gene 1 (RIG-1) signaling pathway to elicit host antiviral innate immunity.