CD140b (PDGFRB) Recombinant Rabbit Monoclonal Antibody (SY10-08), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532047-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532047 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
CD140b (PDGFRB)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P05622, P09619, Q05030
Gene Symbols
Pdgfrb
Immunogen
Recombinant protein within Human PDGF Receptor beta aa 961-1,106
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry, Western Blot
Clone
SY10-08
Conjugate
Unconjugated
Gene
Pdgfrb
Gene Alias
AI528809, Beta platelet-derived growth factor receptor, beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140B, CD140b antigen, IBGC4, IMF1, JTK12, KOGS, PDGF beta chain, PDGF Receptor beta, Pdgfr, Pdgfr1, PDGFR-1, PDGFRB, PDGF-R-beta, PDGFR-beta, PENTT, platelet derived growth factor receptor beta, platelet derived growth factor receptor, beta polypeptide, platelet-derived growth factor receptor 1, Platelet-derived growth factor receptor beta, platelet-derived growth factor receptor beta variant 1, Platelet-derived growth factor receptor, beta, platelet-derived growth factor receptor, beta polypeptide
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18596, 24629, 5159
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- PDGFRB is a receptor tyrosine kinase and has been implicated in atherogenesis and in cell transformation by the SIS oncogene
- These growth factors are mitogens for cells of mesenchymal origin
- The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides
- The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome
- A translocation between chromosomes 5 and 12, that fuses PDGFRB (CD140b) to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.