FGFR1 Recombinant Rabbit Monoclonal Antibody (SD08-25), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532383-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532383 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
FGFR1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P11362
Gene Symbols
FGFR1
Immunogen
Synthetic peptide within Human FGFR1 aa 766-822
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
SD08-25
Conjugate
Unconjugated
Gene
FGFR1
Gene Alias
2.7.10.1, AW208770, Basic fibroblast growth factor receptor 1, basic fibroblast growth factor receptor I, BFGFR, bFGF-R, bFGF-R-1, CD331, CD331 antigen, CEK, CEK1, cek1 protein, cek1 protein precursor, c-fgr, Eask, ECCL, FGF receptor, FGF receptor-1, FGFBR, fgfr 1, Fgfr1, FGFR-1, FGFR1/PLAG1 fusion, FGFR1IIIC, FGFRI, Fibroblast growth factor receptor 1, fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome), fibroblast growth factor receptor 1-IIIc, fibroblast growth factor receptor type 1, Flg, FLT2, FLT-2, FMS-like tyrosine kinase 2, fms-related tyrosine kinase 2, HBGFR, heparin-binding growth factor receptor, HH2, HRTFDS, Hspy, hydroxyaryl-protein kinase, KAL2, LOW QUALITY PROTEIN: fibroblast growth factor receptor 1, MFR, N-sam, OGD, proto-oncogene c-Fgr, Tyrosine kinase receptor CEK1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2260
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family that constitute a family of four membrane-spanning tyrosine kinases (FGFR1-4) which serve as high-affinity receptors for 17 growth factors (FGF1-17)
- The FGF Receptor family plays an important role in multiple biological processes, including mesoderm induction and patterning, cell growth and migration, organ formation and bone growth
- FGFR1 is alternatively spliced generating multiple splice variants that are differentially expressed during embryo development and in the adult body
- Other defects in FGFR1 are responsible for several diseases which include Pfeiffer syndrome (PS), idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), non-syndromic trigonocephaly, Jackson-Weiss syndrome, Antley-Bixler syndrome
- Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.