Calponin 1 Recombinant Rabbit Monoclonal Antibody (SI67-01), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532061-Each-of-1 | In Stock | ₹ 59,185.00 |
PIMA532061 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 59,185.00
GST (18%): ₹ 10,653.30
Total Price: ₹ 69,838.30
Antigen
Calponin 1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P51911, Q08091
Gene Symbols
CNN1
Immunogen
Synthetic peptide within Human Calponin aa 248-297
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Mouse, Porcine, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SI67-01
Conjugate
Unconjugated
Gene
CNN1
Gene Alias
Basic calponin, calponin, calponin 1, calponin 1, basic, smooth muscle, calponin 1, smooth muscle, calponin H1, smooth muscle, Calponin-1, calponins, basic, CN, CNN1, CnnI, epididymis secretory protein Li 14, h1-calponin, HEL-S-14, similar to calponin 1, basic, smooth muscle, Sm-Calp, SMCC, smooth muscle calponin h1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1264, 12797
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction
- It is capable of binding to actin, calmodulin, troponin C and tropomyosin
- Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle
- Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa
- Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract
- The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions
- It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers
- It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma
- Adenoid cystic carcinoma in salivary gland tumors is calponin positive.