PIMA533130

Calponin 1 Recombinant Rabbit Monoclonal Antibody (2H1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533130-Each-of-1 In Stock ₹ 50,596.50

PIMA533130 - Each of 1

₹ 50,596.50

In Stock

Quantity

1

Base Price: ₹ 50,596.50

GST (18%): ₹ 9,107.37

Total Price: ₹ 59,703.87

Antigen

Calponin 1

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P51911, Q08091

Gene Symbols

CNN1

Immunogen

A synthesized peptide derived from human CNN1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone

2H1

Conjugate

Unconjugated

Gene

CNN1

Gene Alias

Basic calponin, calponin, calponin 1, calponin 1, basic, smooth muscle, calponin 1, smooth muscle, calponin H1, smooth muscle, Calponin-1, calponins, basic, CN, CNN1, CnnI, epididymis secretory protein Li 14, h1-calponin, HEL-S-14, similar to calponin 1, basic, smooth muscle, Sm-Calp, SMCC, smooth muscle calponin h1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1264, 12797

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction
  • It is capable of binding to actin, calmodulin, troponin C and tropomyosin
  • Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle
  • Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa
  • Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract
  • The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions
  • It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers
  • It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma
  • Adenoid cystic carcinoma in salivary gland tumors is calponin positive.