Calmodulin Recombinant Rabbit Monoclonal Antibody (SJ16-09), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532074-Each-of-1 | In Stock | ₹ 55,180.00 |
PIMA532074 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,180.00
GST (18%): ₹ 9,932.40
Total Price: ₹ 65,112.40
Antigen
Calmodulin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P0DP23, P0DP24, P0DP25, P0DP26, P0DP27, P0DP28, P0DP29, P0DP30, P0DP31, Q9JM83
Gene Symbols
Calm1, Calm2, CALM3, CALM4, CALM5
Immunogen
Synthetic peptide within Human Calmodulin aa 100-149
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SJ16-09
Conjugate
Unconjugated
Gene
Calm1
Gene Alias
1500001E21Rik, 2310037J09Rik, AI256814, AI327027, AI461935, AI649108, AL024000, AL024017, AY314008, calcium binding gene, DD112, calcium-binding protein Dd112, CALM, CALM 1, CALM1, CALM2, Calm3, Calm4, Calm5, CALML2, Calmodulin, calmodulin 1, calmodulin 1 (phosphorylase kinase, delta), calmodulin 2, calmodulin 2 (phosphorylase kinase, delta), calmodulin 3, calmodulin 3 (phosphorylase kinase, delta), calmodulin 4, calmodulin 5, Calmodulin III, calmodulin-1, Calmodulin-2, calmodulin-3, Calmodulin-4, calmodulin-like, calmodulin-like protein, calmodulin-like protein (neoCaM), caM, CAM1, Cam2, CAM3, CaMA, Camb, CamC, CaMI, CAMII, CAMIII, CPVT4, DD112, DD132, DD312, epididymis secretory protein Li 72, HEL-S-72, hypothetical protein, LP7057 protein, LQT14, LQT15, MGC128137 protein, neo-calmodulin, NeoCaM, PHKD, PHKD2, PHKD3, phosphorylase kinase delta, phosphorylase kinase subunit delta, phosphorylase kinase, delta subunit, prepro-calmodulin 1, prepro-calmodulin 2, prepro-calmodulin 3, R75142, RNCAMIII, Scarf, Scarf2, similar to calmodulin, skin calmodulin-related factor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
12313, 12314, 12315, 24242, 24244, 494124, 50663, 801, 805, 80796, 808
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+
- Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases
- Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis
- Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells
- With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals
- As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins
- It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases
- Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations
- Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found
- They are identified by their occurrence in the cytosol or on membranes facing the cytosol and by a high affinity for calcium
- Calmodulin contains 149 amino acids and has 4 calcium-binding domains
- Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters.