NOTCH1 Recombinant Rabbit Monoclonal Antibody (SJ205), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532080-Each-of-1 | In Stock | ₹ 53,088.50 |
PIMA532080 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,088.50
GST (18%): ₹ 9,555.93
Total Price: ₹ 62,644.43
Antigen
NOTCH1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P46531, Q01705, Q07008
Gene Symbols
Notch1
Immunogen
Synthetic peptide within Human Notch 1 aa 2,481-2,530
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SJ205
Conjugate
Unconjugated
Gene
Notch1
Gene Alias
9930111A19Rik, AOS5, AOVD1, Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila), hN1, lin-12, major type A protein, Mis6, Motch, Motch A, mT14, N1, neurogenic locus notch homolog protein 1, NEXT, NICD, NOTCH, notch 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, Notch gene homolog 1, Notch homolog 1, translocation-associated, notch receptor 1, Notch1, p300, RP23-306D20.12, RP23-306D20.12-001, Tan1, Translocation-associated notch protein TAN-1, transmembrane receptor Notch1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18128, 25496, 4851
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region
- Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures
- The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1
- Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).