CD304 (Neuropilin-1) Recombinant Rabbit Monoclonal Antibody (ST05-30), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532179-Each-of-1 | In Stock | ₹ 47,303.50 |
PIMA532179 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,303.50
GST (18%): ₹ 8,514.63
Total Price: ₹ 55,818.13
Antigen
CD304 (Neuropilin-1)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O14786, P97333, Q9QWJ9
Gene Symbols
NRP1
Immunogen
Synthetic peptide within Human Neuropilin-1 aa 881-923
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone
ST05-30
Conjugate
Unconjugated
Gene
NRP1
Gene Alias
A5 protein, BDCA4, C530029I03, CD304, Neuropilin, neuropilin 1, Neuropilin1, neuropilin-1, Neuropilin-1 precursor (A5 protein), NP1, NP-1, Npn1, NPN-1, NRP, NRP 1, Nrp1, sNRP 1, sNRP1, soluble NRP 1, soluble NRP1, transmembrane receptor, vascular endothelial cell growth factor 165 receptor, VEGF165R
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
18186, 246331, 8829
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain
- Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors
- Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system
- This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis
- Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.