Dysferlin Recombinant Rabbit Monoclonal Antibody (JF05-54), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532524-Each-of-1 | In Stock | ₹ 47,837.50 |
PIMA532524 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,837.50
GST (18%): ₹ 8,610.75
Total Price: ₹ 56,448.25
Antigen
Dysferlin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O75923, Q9ESD7
Gene Symbols
DYSF
Immunogen
Synthetic peptide within Human Dysferlin aa 113-162
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JF05-54
Conjugate
Unconjugated
Gene
DYSF
Gene Alias
2310004N10Rik, AI604795, D6Pas3, Dysf, Dysferlin, dysferlin variant a, dysferlin_a, dystrophy-associated fer-1-like 1, dystrophy-associated fer-1-like protein, FER1L1, fer-1-like family member 1, fer-1-like protein 1, FLJ00175, FLJ90168, LGMD2B, limb girdle muscular dystrophy 2B (autosomal recessive), MMD1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
26903, 8291
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Dysferlin is the protein product of the 2p13 gene that is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM)
- Dysferlin is normally localized to the muscle plasma membrane
- In patients with LGMD2B and MM, immunoreactivity to dysferlin is severely reduced or lost, depending on the type of mutation
- This antibody is used for the characterization of LGMD2B and MM.