PIMA532295

HNF4A Recombinant Rabbit Monoclonal Antibody (SN72-03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532295-Each-of-1 In Stock ₹ 46,947.50

PIMA532295 - Each of 1

₹ 46,947.50

In Stock

Quantity

1

Base Price: ₹ 46,947.50

GST (18%): ₹ 8,450.55

Total Price: ₹ 55,398.05

Antigen

HNF4A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P41235, P49698

Gene Symbols

HNF4A

Immunogen

Synthetic peptide within Human HNF-4-alpha aa 21-70

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SN72-03

Conjugate

Unconjugated

Gene

HNF4A

Gene Alias

alpha transcription factor 4, FLJ39654, FRTS4, hepatic nuclear factor 4 alpha, hepatic nuclear factor 4, alpha, hepatocyte nuclear factor 4 alpha, hepatocyte nuclear factor 4, alpha, hepatocyte nuclear factor 4-alpha, HNF4, Hnf-4, HNF4 alpha, Hnf4a, HNF4a7, HNF4a8, HNF4a9, Hnf4alpha, HNF-4-alpha, HNF4-alpha, HNF4alpha10, HNF4alpha10/11/12, HNF4alpha11, HNF4alpha12, MODY, MODY1, NR2A1, NR2A21, Nuclear receptor 2A1, nuclear receptor subfamily 2 group A member 1, TCF, TCF14, TCF-14, Transcription factor 14, transcription factor HNF-4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

15378, 3172

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor
  • HNF4a is expressed in the liver, kidney, intestine, and pancreas
  • Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1)
  • HNF4 binds to DNA as an exclusive homodimer
  • The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.