SIRT2 Recombinant Rabbit Monoclonal Antibody (JJ08-83), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532451-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532451 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
SIRT2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q5RJQ4, Q8IXJ6
Gene Symbols
SIRT2
Immunogen
Synthetic peptide within Human SIRT2 aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
JJ08-83
Conjugate
Unconjugated
Gene
SIRT2
Gene Alias
5730427M03Rik, 5E5 antigen, mSIR2L2, NAD-dependent deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, silent information regulator 2, silent mating type information regulation 2, (S.cerevisiae, homolog)-like, sirtuin 2, SIR2, SIR2L, SIR2L2, SIR2-like protein 2, sir2-related protein type 2, Sirt2, sirtuin 2, sirtuin type 2, sirtuin-2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
22933, 361532
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair
- It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells
- SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise
- SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.