IGF2 Recombinant Rabbit Monoclonal Antibody (JJ092-3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532485-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532485 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
IGF2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P01344
Gene Symbols
IGF2
Immunogen
Recombinant protein within Human IGF2 aa 25-121
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JJ092-3
Conjugate
Unconjugated
Gene
IGF2
Gene Alias
AL033362, C11orf43, FLJ22066, FLJ44734, GRDF, H-IGF-2, IGF, Igf2, Igf-2, IGFII, Igf-II, Insulin like growth factor, insulin like growth factor 2, insulin-like growth factor 2, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor II (IGF-II), Insulin-like growth factor II (somatomedin A), Insulin-like growth factor II Ala-25 Del, insulin-like growth factor II isoform 2 variant 4 preprotein, insulin-like growth factor type 2, M6pr, Mpr, MSA, multiplication-stimulating activity, Multiplication-stimulating polypeptide, Peg2, PP1446, PP9974, preptin, RNIGF2, Somatomedin-A, T3M-11-derived growth factor
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3481
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The IGFs are mitogenic, polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro
- IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times
- The IGFs belong to the Insulin gene family, which also contains insulin and relaxin
- The IGFs are similar to insulin by structure and function, but have a much higher growth-promoting activity than insulin
- IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone
- Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor
- Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions.