PIMA533046
Thyroid Peroxidase Recombinant Rabbit Monoclonal Antibody (RM368), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533046-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA533046 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Thyroid Peroxidase
Classification
Recombinant Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P07202
Gene Symbols
TPO
Immunogen
A peptide corresponding to the C-terminus of human TPO (Thyroid peroxidase).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM368
Conjugate
Unconjugated
Gene
TPO
Gene Alias
EC 1.11.1, LOW QUALITY PROTEIN: thyroid peroxidase, MSA, TDH2A, thyroid microsomal antigen, thyroid peroxidase, thyroid peroxidase (332 AA), thyroperoxidase, TPO, TPX, TPXEC 1.11.1.8
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
7173
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human TPO (Thyroid peroxidase)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Thyroid Peroxidase is a gene that encodes for a membrane-bound glycoprotein, which functions as an enzyme and plays a crucial role in the proper functioning of the thyroid gland
- This protein is responsible for the iodination of tyrosine residues in thyroglobulin and the formation of phenoxy-ester between pairs of iodinated tyrosines, which leads to the production of thyroid hormones such as thyroxine and triiodothyronine
- Mutations in this gene are known to cause several disorders related to thyroid hormone production, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA
- Several transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants remains undetermined
- Diseases associated with TPO include Thyroid Dyshormonogenesis 2A and Congenital Hypothyroidism.