PIMA534929
DAPK1 Monoclonal Antibody (12B2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534929-Each-of-1 | In Stock | ₹ 46,947.50 |
PIMA534929 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,947.50
GST (18%): ₹ 8,450.55
Total Price: ₹ 55,398.05
Antigen
DAPK1
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P53355
Gene Symbols
DAPK1
Immunogen
Recombinant protein within Human DAP Kinase 1 aa 447-683
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
12B2
Conjugate
Unconjugated
Gene
DAPK1
Gene Alias
D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1612
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: Rat brain tissue, rat lung tissue, human lung cancer tissue, human skin tissue, mouse liver tissue
- DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor
- DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy
- It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting
- Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent
- DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function
- It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.