Nkx2.1 Recombinant Rabbit Monoclonal Antibody (RM373), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533074-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA533074 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Nkx2.1
Classification
Recombinant Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P43699
Gene Symbols
NKX2-1
Immunogen
A peptide corresponding to the N-terminus of human TTF1 (Thyroid transcription factor 1) (Homeobox protein Nkx-2.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM373
Conjugate
Unconjugated
Gene
NKX2-1
Gene Alias
AV026640, BCH, BHC, homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NK-2, NK2 homeobox 1, NK-2 homolog A, NKX2.1, Nkx-2.1, NKX2-1, NKX2A, NMTC1, RNA polymerase I transcription termination factor, T/EBP, TEBP, Thyroid nuclear factor 1, thyroid transcription factor 1, thyroid transcription factor 1 TTF-1 NK-2, thyroid transcription factor 1-like, thyroid-specific enhancer-binding protein, tinman, TITF1, TTF1, TTF-1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
7080
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human TTF1 (Thyroid transcription factor 1) (Homeobox protein Nkx-2.1)
- It may also react to mouse and rat TTF1, as predicted by immunogen homology
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This gene encodes a protein initially identified as a thyroid-specific transcription factor
- The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis
- Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer
- Multiple transcript variants encoding different isoforms have been found for this gene.