Doublecortin Monoclonal Antibody (3 e1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533102-Each-of-1 | In Stock | ₹ 51,842.50 |
PIMA533102 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,842.50
GST (18%): ₹ 9,331.65
Total Price: ₹ 61,174.15
Antigen
Doublecortin
Classification
Monoclonal
Concentration
∽1.0 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
O43602, O88809, Q9ESI7
Gene Symbols
DCX
Immunogen
Full length recombinant human protein expressed in and purified from E. coli
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
3 e1
Conjugate
Unconjugated
Gene
DCX
Gene Alias
DBCN, Dbct, DC, Dcn, DCX, doublecortex, doublecortin, doublin, lissencephalin-X, lissencephaly, X-linked (doublecortin), LISX, Lis-X, LIS-XD, Neuronal migration protein doublecortin, OTTHUMP00000023860, OTTHUMP00000216316, SCLH, XLIS
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
13193, 1641, 787968, 84394
Content And Storage
-20°, C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation
- DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules
- It contains two doublecortin domains, which bind microtubules
- In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex
- Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.