Phospho-PAK1/2/3 (Ser139, Ser141, Ser144) Recombinant Rabbit Monoclonal Antibody (3H12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533185-Each-of-1 | In Stock | ₹ 50,596.50 |
PIMA533185 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,596.50
GST (18%): ₹ 9,107.37
Total Price: ₹ 59,703.87
Antigen
Phospho-PAK1/2/3 (Ser139, Ser141, Ser144)
Classification
Recombinant Monoclonal
Concentration
0.85 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
O75914, Q13153, Q13177
Gene Symbols
Pak1, PAK2, PAK3
Immunogen
A synthesized peptide derived from human Phospho-PAK1/PAK2/PAK3 (S144+S141+S139)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone
3H12
Conjugate
Unconjugated
Gene
PAK3
Gene Alias
5330420P17Rik, A130002K10Rik, activated protein kinase alpha, ADRB2, adriamycin resistance-associated, AI836325, Alpha-PAK, ARA, AW045634, Beta-PAK, bPAK, CDC42/RAC effector kinase PAK-A, CDC42/RAC effector kinase PAK-B, CDKN1A, C-t-PAK2, D16Ertd269e, EC 2.7.11.1, gamma pak, gamma-PAK, hPAK3, kinase PAK1, mKIAA4182, MRX30, MRX47, oligophrenin-3, OPHN3, p21 (CDKN1A)-activated kinase 1, p21 (CDKN1A)-activated kinase 2, p21 (CDKN1A)-activated kinase 3, p21 (RAC1) activated kinase 1, p21 (RAC1) activated kinase 2, p21 (RAC1) activated kinase 3, p21 protein (Cdc42/Rac)-activated kinase 1, p21 protein (Cdc42/Rac)-activated kinase 2, p21 protein (Cdc42/Rac)-activated kinase 3, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related), p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related), p21-activated kinase 1, p21-activated kinase 2, p21-activated kinase 3, p27, p34, p58, p65-PAK, p68-PAK, PAK 1, PAK alpha, PAK beta, PAK gamma, Pak1, PAK-1, Pak2, PAK-2, PAK-2p27, PAK-2p34, PAK3, PAK-3, PAK3beta, PAK65, Pak65alpha, Pak65beta, Paka, PAKalpha, Pakb, PAKgamma, Protein kinase MUK2, S6/H4 kinase, Serine/threonine-protein kinase PAK 1, serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase PAK 3, STE20 homolog, yeast, Stk4
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5058, 5062, 5063
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Related Products
Description
- In mammals, there are several identified isoforms of p21-Activated Protein Kinases or PAKs: alpha-PAK (also known as PAK-1) and beta-PAK (also known as PAK-3) are mostly brain-specific, while gamma-PAK (also known as PAK-2) is expressed ubiquitously (Jakobi et al., 2003)
- Mutations of the gene coding for PAK-3 are associated wit X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004)
- PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death (Jakobi et al., 2003; Walter et al., 1998)
- Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK (Jakobi et al., 2000).