CaMKIV Recombinant Rabbit Monoclonal Antibody (JB33-13), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534720-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA534720 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
CaMKIV
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q16566
Gene Symbols
CAMK4
Immunogen
Recombinant protein within Human CAMKIV aa 360-473
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JB33-13
Conjugate
Unconjugated
Gene
CAMK4
Gene Alias
A430110E23Rik; AI666733; brain Ca(2+)-calmodulin-dependent protein kinase type IV; brain Ca++-calmodulin-dependent protein kinase type IV; Ca2+/calmodulin-dependent protein kinase type IV/Gr; Calcium/calmoduli; calcium/calmodulin dependent protein kinase IV; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase IV L homeolog; calcium/calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain; Calmodulin-dependent protein kinase IV; calspermin; CAM kinase- GR; CAM kinase IV; CAM kinase-GR; CAMK; CaMK IV; camk4; camk4.L; camk4-A; CAMK-GR; CAMKIV; CaMKIV/Gr; Ccdpk; D18Bwg0362e; EC 2.7.11.17; KCC4; kinase CaMK4; OTTHUMP00000222818; RATCCDPK; xCaM; XELAEV_18008011mg
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
814
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: 293T, Hela, SH-SY-5Y, rat brain tissue, human tonsil tissue, mouse brain tissue
- CAMK4 (CaMKIV) is a serine/threonine protein kinase that phosphoryates CREB, oncoprotein 18, and SRF
- It has limited tissue distribution, and has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells
- The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression
- CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees
- In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects
- In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT)
- CaMKIV is encoded, along with calspermin, by the CaMKIV gene
- It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin
- The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.