PKC delta Recombinant Rabbit Monoclonal Antibody (JJ093-02), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532482-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532482 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
PKC delta
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P09215, P28867, Q05655
Gene Symbols
PRKCD
Immunogen
Recombinant protein within mouse PKC delta aa 525-671
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JJ093-02
Conjugate
Unconjugated
Gene
PRKCD
Gene Alias
1-May, AI385711, ALPS3, CVID9, D14Ertd420e, kinase nPKC-delta, KPCD, MAY1, nPKC-delta, PKC[d], Pkcd, PKCdelta, Prkcd, protein kinase C delta, protein kinase C delta type, Protein kinase C delta type catalytic subunit, Protein kinase C delta type regulatory subunit, protein kinase C delta variant IX, protein kinase C delta VIII, protein kinase C, delta, protein kinase C, delta IV, protein kinase C, delta V, protein kinase C[d], SDK1, Sphingosine-dependent protein kinase-1, Tyrosine-protein kinase PRKCD
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
170538, 18753, 5580
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The PKC family of serine/threonine kinases, including PRKCD (PKC delta), is activated intracellularly by signal transduction pathways
- In humans, at least 12 different PKC polypeptides have been identified
- These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
- PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
- Protein kinase C (PKC) can be activated by calcium and the second messenger diacylglycerol
- PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways
- PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters
- Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells
- The protein encoded by this gene is one of the PKC family members
- Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types
- Alternatively spliced transcript variants encoding the same protein have been observed.