PIMA534774

SMN1 Recombinant Rabbit Monoclonal Antibody (JG38-19), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA534774-Each-of-1 In Stock ₹ 47,481.50

PIMA534774 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

SMN1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q16637

Gene Symbols

SMN1

Immunogen

Recombinant protein within Human Gemin aa 83-220

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

JG38-19

Conjugate

Unconjugated

Gene

SMN1

Gene Alias

AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6606

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form

Liquid

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Description

  • Positive Control: SiHa, rat testis tissue, mouse brain tissue
  • The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13
  • This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions
  • The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region
  • The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein
  • The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome
  • Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.