PIMA547623

Phospho-CRMP2 (Thr555) Monoclonal Antibody (M539), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547623-Each-of-1 In Stock ₹ 46,769.50

PIMA547623 - Each of 1

₹ 46,769.50

In Stock

Quantity

1

Base Price: ₹ 46,769.50

GST (18%): ₹ 8,418.51

Total Price: ₹ 55,188.01

Antigen

Phospho-CRMP2 (Thr555)

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

O08553, P47942, Q16555

Gene Symbols

DPYSL2

Immunogen

Clone M539 was generated from a phospho-CRMP2 (Thr-555) synthetic peptide (coupled to carrier protein) corresponding to amino acids surrounding Thr-555 in human CRMP2. This sequence is conserved in rat and mouse CRMP2 and the phospho-site is not conserved in other CRMP family members.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Western Blot

Clone

M539

Conjugate

Unconjugated

Gene

DPYSL2

Gene Alias

AI851130; collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP2; CRMP-2; DHPRP2; dihydropyrimidinase like 2; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; DPYL2; Dpysl2; DRP2; DRP-2; Musunc33; N2A3; Neural-specific protein NSP60; TOAD-64; turned on after division 64; turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP2; ULIP-2; unc-33-like phosphoprotein 2; Unknown (protein for MGC:137406)

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12934, 1808, 25416

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

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Description

  • The antibody detects a 70 kDa* protein corresponding to CRMP2 on immunoblots of rat PC12 or mouse C2C12 cells treated with calyculin A
  • This reactivity is not observed after lambda phosphatase dephosphorylation of Thr-555
  • Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton
  • Plays a role in axon guidance, neuronal growth cone collapse and cell migration.