PIPA129843

IL21R Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA129843-Each-of-1 In Stock ₹ 48,905.50

PIPA129843 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

IL21R

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il21r

Gene Alias

CD360; IL-21 receptor; Il21r; IL-21R; interleukin 21 receptor; interleukin-21 receptor; LR-beta; lymphocyte receptor beta; MGC10967; NILR; novel cytokine receptor 8; Novel interleukin receptor; NR8; UNQ3121/PRO10273

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

50615

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.2% gelatin and 0.05% sodium azide

Gene Accession No.

Q9HBE5

Gene Symbols

Il21r

Immunogen

Synthetic peptides (CSLHRSAHNATHATYT & CDFTSPGDEGPPRSYLR) corresponding to amino acids 65-80 and 505-521 of Human IL21R respectively.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Description PA1-29843 detects IL21-R from human samples
  • The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21)
  • It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5)
  • This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells
  • The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3
  • Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production
  • Three alternatively spliced transcript variants encoding the same protein have been described.