PIPA5102961

MESDC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102961-Each-of-1 In Stock ₹ 41,607.50

PIPA5102961 - Each of 1

₹ 41,607.50

In Stock

Quantity

1

Base Price: ₹ 41,607.50

GST (18%): ₹ 7,489.35

Total Price: ₹ 49,096.85

Antigen

MESDC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mesd

Gene Alias

2210015O11Rik; AW537813; BOCA; KIAA0081; LDLR chaperone MESD; LRP chaperone MESD; MESD; Mesdc2; MESDM; mesoderm development candiate 2; mesoderm development candidate 2; Mesoderm development LRP chaperone MESD; Mesoderm development protein; mKIAA0081; msd; renal carcinoma antigen NY-REN-61; UNQ1911/PRO4369

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23184, 67943

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q14696, Q9ERE7

Gene Symbols

Mesd

Immunogen

A synthesized peptide derived from human MESDC2(Accession Q14696), corresponding to amino acid residues A34-H84.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total MESDC2
  • MESDC2 chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs)
  • Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane
  • Essential for specification of embryonic polarity and mesoderm induction
  • Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4
  • May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.