DUSP3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103034-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103034 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
DUSP3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Dusp3
Gene Alias
2210015O03Rik; 5031436O03Rik; dual specificity phosphatase 3; dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related); dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)-like; dual specificity protein phosphatase 3; Dual specificity protein phosphatase VHR; DUSP 3; DUSP3; DUSP-3; RGD1560049; serine/threonine specific protein phosphatase; T-DSP11; Vaccinia H1-related phosphatase; vaccinia virus phosphatase VH1-related; VHR
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1845, 72349
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P51452, Q9D7X3
Gene Symbols
Dusp3
Immunogen
A synthesized peptide derived from human DUSP3(Accession P51452), corresponding to amino acid residues M1-I48.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total DUSP3
- Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins
- Together with tyrosine kinases, PTPs regulate the phosphorylation state of many important signaling molecules, such as the MAP kinase family
- Recently, increasing attention has been focused on the growing family of PTPs
- Like PTKs, PTPs have been implicated in cell signaling, cell growth and proliferation, and oncogenic transformation
- Moreover, some PTPs can be involved in cell cycle regulation and embryogenesis
- Dual specificity phosphatases (DSPs) are an emerging subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which appears to be selective for dephosphorylating the critical phosphothreonine and phosphotyrosine residues
- The prototypical DSP is the VH1 gene in vaccinia virus expressed in late-stage viral infection
- A shallow active site pocket in VHR allows for the hydrolysis of phosphorylated serine, threonine, or tyrosine protein residues, whereas the deeper active site of protein tyrosine phosphatases (PTPs) restricts substrate specificity to only phosphotyrosine.