KDM5A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5103448-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5103448 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
KDM5A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KDM5A
Gene Alias
AA409370; C76986; histone demethylase JARID1A; JARID1A; jumonji, AT rich interactive domain 1A (Rbp2 like); Jumonji, AT rich interactive domain 1A (RBP2-like); jumonji/ARID domain-containing protein 1A; Kdm5a; lysine (K)-specific demethylase 5A; lysine demethylase 5A; lysine-specific demethylase 5A; Rbbp2; RBBP-2; RBP2; retinoblastoma binding protein 2; retinoblastoma-binding protein 2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
214899, 5927
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P29375, Q3UXZ9
Gene Symbols
KDM5A
Immunogen
A synthesized peptide derived from human KDM5A(Accession P29375), corresponding to amino acid residues E1384-V1434.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total KDM5A
- UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance
- The protein is one of two functional homologs to yeast Upf3p
- This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein
- It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctionsThis gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance
- The encoded protein is one of two functional homologs to yeast Upf3p
- mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD)
- When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons
- This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein
- It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions
- This gene is located on the long arm of chromosome X
- Two splice variants encoding different isoforms have been found for this gene.