PIPA5103716

CATSPER3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103716-Each-of-1 In Stock ₹ 46,502.50

PIPA5103716 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

CATSPER3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CATSPER3

Gene Alias

4921522D01Rik; Ca(v)-like protein; CACRC; calcium channel repeat containing 1; cation channel sperm associated 3; cation channel sperm-associated protein 3; cation channel, sperm associated 3; CatSper3; One-repeat calcium channel-like protein; putative ion channel CatSper3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

347732, 76856

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q80W99, Q86XQ3

Gene Symbols

CATSPER3

Immunogen

A synthesized peptide derived from human CATSPER3(Accession Q86XQ3), corresponding to amino acid residues L183-Q233.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total CATSPER3
  • CatSpers (cation channel, sperm associated proteins) are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail
  • CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm
  • There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4
  • CatSper proteins contain a single, six-transmembrane-spanning segment and exhibit the voltage-dependent Ca2+ channel four-repeat structure
  • CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel
  • Mutations in any of the genes encoding CatSper family proteins can result in male infertility
  • CatSper3 plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization.