Phospho-LIMK1/LIMK2 (Thr508, Thr505) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104924-Each-of-1 | In Stock | ₹ 41,518.50 |
PIPA5104924 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,518.50
GST (18%): ₹ 7,473.33
Total Price: ₹ 48,991.83
Antigen
Phospho-LIMK1/LIMK2 (Thr508, Thr505)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LIMK1
Gene Alias
KIZ-1, LIM domain kinase 1, LIM domain kinase 2, lim kinase 1, LIM kinase 2, LIM motif-containing protein kinase, LIM motif-containing protein kinase 1, LIM motif-containing protein kinase 2, LIM-domain containing protein kinase 1, LIM-domain containing, protein kinase, LIM-domain containing, protein kinase 1, Limk, LIMK 2, LIMK1, LIMK-1, LIMK2, LIMK-2, Limk2b, Link2
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16885, 16886, 29524, 3984, 3985, 65172
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O54785, P53667, P53668, P53669, P53670, P53671
Gene Symbols
LIMK1, LIMK2
Immunogen
A synthesized peptide derived from human LIMK1(Accession P53667), corresponding to amino acid residues around phosphorylated Thr508.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of LIMK1/2 only when phosphorylated at Threonine 508/505
- Proteins containing LIM motifs are typically involved in cell fate determination and growth control
- A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified
- LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis
- LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation
- Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development
- A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.