Phospho-CAMKIV (Thr200) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105011-Each-of-1 | In Stock | ₹ 45,078.50 |
PIPA5105011 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,078.50
GST (18%): ₹ 8,114.13
Total Price: ₹ 53,192.63
Antigen
Phospho-CAMKIV (Thr200)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CAMK4
Gene Alias
A430110E23Rik; AI666733; brain Ca(2+)-calmodulin-dependent protein kinase type IV; brain Ca++-calmodulin-dependent protein kinase type IV; Ca2+/calmodulin-dependent protein kinase type IV/Gr; Calcium/calmoduli; calcium/calmodulin dependent protein kinase IV; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase IV L homeolog; calcium/calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain; Calmodulin-dependent protein kinase IV; calspermin; CAM kinase- GR; CAM kinase IV; CAM kinase-GR; CAMK; CaMK IV; camk4; camk4.L; camk4-A; CAMK-GR; CAMKIV; CaMKIV/Gr; Ccdpk; D18Bwg0362e; EC 2.7.11.17; KCC4; kinase CaMK4; OTTHUMP00000222818; RATCCDPK; xCaM; XELAEV_18008011mg
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12326, 25050, 814
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P08414, P13234, Q16566
Gene Symbols
CAMK4
Immunogen
A synthesized peptide derived from human CAMK4(Accession Q16566), corresponding to amino acid residues around phosphorylated Thr200.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of CaMK4 only when phosphorylated at Threonine 200
- CAMK4 (CaMKIV) is a serine/threonine protein kinase that phosphoryates CREB, oncoprotein 18, and SRF
- It has limited tissue distribution, and has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells
- The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression
- CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees
- In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects
- In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT)
- CaMKIV is encoded, along with calspermin, by the CaMKIV gene
- It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin
- The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.