Phospho-WNK1 (Thr60) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105033-Each-of-1 | In Stock | ₹ 45,345.50 |
PIPA5105033 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,345.50
GST (18%): ₹ 8,162.19
Total Price: ₹ 53,507.69
Antigen
Phospho-WNK1 (Thr60)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
WNK1
Gene Alias
6430573H23Rik; EG406236; Erythrocyte 65 kDa protein; HSAN2; HSN2; hWNK1; KDP; KIAA0344; Kinase deficient protein; MGC163339; MGC163341; mKIAA0344; p65; PPP1R167; Prkwnk1; prostate-derived sterile 20-like kinase; protein kinase lysine-deficient 1; Protein kinase with no lysine 1; protein phosphatase 1, regulatory subunit 167; PSK; Serine/threonine-protein kinase WNK1; serine/threonine-protein kinase WNK1 1; serine/threonine-protein kinase WNK1 2; With no K; WNK lysine deficient protein kinase 1; WNK lysine deficient protein kinase 1 isoform; WNK1
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116477, 232341, 65125
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P83741, Q9H4A3, Q9JIH7
Gene Symbols
WNK1
Immunogen
A synthesized peptide derived from human WNK1(Accession Q9H4A3), corresponding to amino acid residues around phosphorylated Thr60.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of WNK1 only when phosphorylated at Threonine 60
- WNK1 serine/threonine kinase is a member of the WNK subfamily
- WNK1 may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions
- Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II
- WNK plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation
- Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively
- Activates SCNN1A, SCNN1B, SCNN1D, and SGK1
- WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron
- Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.