PIPA5105023

Phospho-BAD (Ser99) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105023-Each-of-1 In Stock ₹ 46,502.50

PIPA5105023 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-BAD (Ser99)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BAD

Gene Alias

AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12015, 572, 64639

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O35147, Q61337, Q92934

Gene Symbols

BAD

Immunogen

A synthesized peptide derived from mouse BAD(Accession Q92934), corresponding to amino acid residues around phosphorylated Ser99.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of BAD only when phosphorylated at Ser136 of mouse BAD or Ser99 of human BAD
  • The protein encoded by BAD is a member of the BCL-2 family
  • BCL-2 family members are known to be regulators of programmed cell death
  • This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity
  • Proapoptotic activity of this protein is regulated through its phosphorylation
  • Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein
  • Alternative splicing of this gene results in two transcript variants which encode the same isoform.