PIPA5105162

Phospho-OPRK1 (Tyr369) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105162-Each-of-1 In Stock ₹ 46,502.50

PIPA5105162 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Phospho-OPRK1 (Tyr369)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OPRK1

Gene Alias

kappa opioid receptor; kappa-type opioid receptor; KOPR1; KOR; K-OR-1; KOR-1; MSL-1; Opiate receptor, kappa-1; opioid receptor kappa 1; opioid receptor, kappa 1; opioid receptor, kappa 2; OPRK; OPRK1; Oprk2; Ork1; R21; Ror-d

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18387, 29335, 4986

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P33534, P34975, P41145

Gene Symbols

OPRK1

Immunogen

A synthesized peptide derived from human OPRK1(Accession P41145), corresponding to amino acid residues around phosphorylated Tyr369.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of OPRK1 only when phosphorylated at Tyr369
  • This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family
  • It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids
  • Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release
  • This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids
  • Variations in this gene have also been associated with alcohol dependence and opiate addiction
  • Alternatively spliced transcript variants encoding different isoforms have been found for this gene
  • A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.