PIPA5105557

Phospho-MARCKS (Ser27) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105557-Each-of-1 In Stock ₹ 46,680.50

PIPA5105557 - Each of 1

₹ 46,680.50

In Stock

Quantity

1

Base Price: ₹ 46,680.50

GST (18%): ₹ 8,402.49

Total Price: ₹ 55,082.99

Antigen

Phospho-MARCKS (Ser27)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MARCKS

Gene Alias

80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17118, 25603, 4082

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P26645, P29966, P30009

Gene Symbols

MARCKS

Immunogen

A synthesized peptide derived from human MARCKS(Accession P29966), corresponding to amino acid residues around phosphorylated Ser27.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of MARCKS only when phosphorylated at Ser27
  • MARCKS is a substrate for protein kinase C
  • It is localized to the plasma membrane and is an actin filament crosslinking protein
  • Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm
  • The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.